Unexplained weight gain and weight loss can also signal a major issue with your health, says Dr. Julie Chen, an integrative physician and health expert. Don't ignore them. If you unexpectedly gain a lot of weight, this can signify hypothyroidism, adrenal disorders like Cushing's syndrome, fluid retention as in congestive heart failure or renal disease, and pregnancy.
If you unexpectedly lose a lot of weight, this can signify cancer, hyperthyroidism, autoimmune diseases, chronic diseases, and depression.