Your stomach can go from holding 50 milliliters (that's less than a shot glass) when empty to up to four liters (a little more than a gallon of milk) when full. But you'll usually top out at 1 to 1.5 liters, the point at which most people are comfortably satisfied. “Once you consume more than this, you really start stretching the stomach wall, which causes discomfort and distention that could last a few hours,” says Ed Levine, M.D., a Connecticut-based gastroenterologist. Keep consistently overstuffing yourself, and over time your belly will adapt, growing to accommodate more and more food and liquid. “If you eat 2 liters per meal regularly, you might feel miserable the first few times, but after several months, your stomach muscles will eventually stretch out," Levine says. And they won't shrink back to their normal size, meaning you'll need even more food to feel full. [Tweet this scary fact!] Obesity 101, folks.