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Do the Jet Lag Workout.

Exercising the morning after your arrival can help you adjust to the new time zone faster, says Karyn Esser, Ph.D., a professor of physiology and functional genomics at the University of Florida. That's because your muscles have their own internal clocks, and they respond to movement rather than light, she says. Working out tells them that it's daytime, which lets you sync physiologically to your new time zone. Esser suggests doing some cardio for at least 30 minutes. (Up Next: The Brilliant Way to Cure Jet Lag with Food.)

Need a vacay? Check out some of these gorgeous vacation destinations that make relaxation first priority.

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Cure Travel Insomnia.

The first night of vacation, we tend to sleep 20 to 25 percent less than usual, according to Brown University researchers, who have dubbed this phenomenon "first-night effect." "Part of your brain refuses to drift off, acting as a night watchman to protect you from harm," says Yuka Sasaki, Ph.D., an associate professor at Brown. To trick your mind into letting down its defenses, bring pillowcases from home and put on your usual night cream before bed. The familiar textures and smells may reduce the feeling of unfamiliarity, so you might snooze easier. (Or you can try these Incredibly Weird and Wacky Insomnia Cures.)

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Switch On Your Vacation Mind.

When you finally reach your destination, it can take a full 24 hours to relax enough to enjoy yourself. That's wasted time. Since every minute of your trip is precious, use this speedy meditation trick from Beverly Fox-Crismond, the spa director at One Ocean Resort & Spa in Florida, to immediately find your Zen. (Try this 20-Minute Guided Meditation for Beginners that will melt your stress away.)

Look. Find a peaceful spot, and settle in for a few seconds. Then gaze out into the distance, taking in the sights around you, but don't zero in on any one thing. This will begin to quiet the part of your brain that's still hung up on the tension from the day.

Breathe. Take a few deep, slow breaths. As you exhale, feel the lingering anxiety drain from your body.

Listen. Focus on nearby sounds. If you're on the beach, tune in to the crashing waves; in the woods, listen to the chirping birds. This will bring you fully into the present moment and make you feel calm and happy.

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Let Your Body Loose.

As soon as you get off the plane or out of your car, do this move: Grab your left thigh with both hands and gently twist it inward, as if you're trying to move the muscle around your thigh bone. Hold for two to three seconds, then release, twist outward, and hold again. Repeat three or four times, then do the entire sequence on your right thigh. "When you sit for prolonged periods, the connective tissue in the back of your thighs becomes compressed and dehydrated," says Sue Hitzmann, an exercise physiologist and the creator of the MELT Method, a pain-reduction program. "The constriction can make your lower back ache and decrease blood flow to your core, causing whole-body stiffness and fatigue," she explains. "The twisting stretch quickly decompresses the tissue and restores blood flow to ease the aches and pain and boost your energy."

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Don't Let Germs Take You Down.

That neck pillow you fly with? It's a hot spot for bacteria. While you snooze, it's picking up all kinds of germs and dust mites left on the headrest by previous passengers, says Philip M. Tierno, Ph.D., a clinical professor of microbiology and pathology at the New York University School of Medicine. Now, every time you use it, you expose yourself to bugs and allergens from past flights. Lesson: Decontaminate. Throw the pillow cover into the wash after each trip without fail. If it doesn't have a cover, vacuum the cushion or spritz it with a germicide that contains alcohol, such as Lysol Disinfectant Spray ($5). (Psst...7 Things You're Not Washing (But Should Be).)

Photo: Lysol