Tap into these hormones to take your workout to the next level.
exercise hormones

Every time you exercise, special hormones in your body spring into action. Released by your system when you move, they give you energy, spark your motivation, and boost your mood. "Hormones are essential for your ability to work out effectively," says Katarina Borer, Ph.D., a professor of movement science and the director of the Exercise Endocrinology Laboratory at the University of Michigan. "They improve your heart and lung function, they bring fuel to your muscles, and they help your body recover afterward." Even so, these exercise hormones are virtually unknown and underappreciated-but that's about to change.


This hormone is produced by your bones when you work out. Its job: to encourage your muscles to absorb the nutrients that help them perform at their peak. "In women, though, osteocalcin production begins to decrease around age 30," says Gerard Karsenty, Ph.D., chair of the genetics and development department at Columbia University Medical Center. As levels drop off, he says, your nutrient-depleted muscles can't work as hard.

Fortunately, regular exercise may bump up your production of osteocalcin, and that extra boost can elevate your performance, Karsenty says. His research found that women's levels were higher after they worked out for 45 minutes; in another study, the muscles of animals that were given a dose of the hormone functioned as effectively as those a fraction of their age. Hit the gym at least every other day to keep your levels up, Karsenty suggests. (Guess what else boosts osteocalcin? EVOO.)


Your brain prompts the release of this powerful stress hormone when you work out. And that's a good thing: "Noradrenaline stimulates the metabolism and helps your heart and lungs respond properly to exercise," says Jill Kanaley, Ph.D., a professor and associate chair of nutrition and exercise physiology at the University of Missouri. It also makes you more resilient to mental stress. In addition, noradrenaline helps turn white fat into brown, just like irisin, according to a study from Brigham and Women's Hospital in Boston.

The longer or harder you move, the more noradrenaline you produce, Borer says. Your best bet: Add short, super-high-intensity bursts to your regular routines. (Surprisingly, noradrenaline is also one reason why make-up sex is so steamy.)

Peptide YY

The gut secretes this to help you feel full. But exercise also triggers the production of peptide YY (PYY), according to research in the journal Appetite. "People who exercise more frequently produce more PYY than others, but levels can rise after a single workout," says Leslie J. Bonci, R.D.N., a board-certified sports dietitian and a sports nutrition adviser to Klean Athlete. The relationship between PYY and hunger is complex: "You might feel ravenous immediately after exercising but less hungry an hour later as levels of the hormone continue to climb," Bonci says. Overall, though, you'll feel more satisfied with smaller portions. (Here are more tips on how to keep your post-workout hunger in check.)

Weight-bearing aerobic exercises, like jumping rope and playing tennis, are the most effective at suppressing appetite, research indicates. Experts aren't sure why, but it may be because these activities engage your gut, where PYY is produced. You can maximize that effect by eating about 0.6 to 0.8 grams of protein per pound of body weight daily, Bonci says. "People with diets that are higher in protein tend to produce extra PYY," she explains.

Growth Factors

These include hormones as well as hormone-like substances that help build your muscles-and your brain-power too. When you work out, the body releases hormones such as insulin-like growth factor-1 (IGF-1) and vascular endothelial growth factor (VEGF), along with proteins like brain-derived neurotrophic factor (BDNF). (ICYMI, growth hormone is one of the most important hormones for weight loss.)

"IGF-1 and VEGF help repair the muscle damage caused by exercise, helping to build the fibers back stronger," says Kanaley. The growth factors may also strengthen your memory and cognitive function. Different types of workouts are best at boosting each growth factor, Borer says. HIIT exercises raise VEGF, lifting heavy weights raises IGF-1, and high-intensity endurance aerobic activities like running raise BDNF levels. To score all three, change up your routine regularly. (Fun fact: There's a totally different hormone responsible for your runner's high.)


This increases the activity of the genes that convert white-fat cells into brown, a beneficial type of fat that can burn calories, according to researchers from the University of Florida College of Medicine. Irisin may reduce white-fat stores too: Tissue samples that were exposed to irisin had up to 60 percent fewer mature fat cells than others, the study authors say.

Workouts that target large muscle groups like your glutes, quads, or chest typically release more irisin than exercises that work smaller muscles such as biceps or calves, since bigger muscles contain more of the hormone, Bonci says. She suggests endurance activities such as running or high-intensity strength workouts like CrossFit.

There's also evidence that increasing levels of melatonin, the sleep hormone, bumps up the production of irisin. Eating melatonin-rich foods like walnuts and tart cherries before bed will help you sleep better and burn more fat, Bonci says.