9 Hair Loss Treatments That Could Change Everything

Nutrafol offers hair loss solutions for all. With seven formulas available, the company uses natural ingredients to combat hair thinning for a range of circumstances. Those assigned female at birth can choose from a vegan formula, a general formula geared towards ages 18 to 44, a specialized formula for those over the age of 45, and a postpartum formula perfect for those who recently gave birth.

Alternatively, those who are assigned male at birth can choose from a supplement designed to target early signs of hair loss, a kit that specifically targets thinning along the hairline, and another kit that is perfect for excess shedding. Its expansive approach to hair loss, impressive clinical results, and emphasis on plant-based ingredients make Nutrafol's products the best oral supplements for hair loss. 

Users trusts Nutrafol’s ability to create effective treatments, both due to its excellent customer reviews and its expansive board of scientific advisors. The founders have a personal connection to the brand, with all three of them having experienced the difficulties of hair loss.

While each formula boasts different active ingredients, you can expect to see results from ingredients like marine collagen, biotin, mava powder, saw palmetto, and curcumin. Plenty of these ingredients pull double duty, with Nutrafol claiming some formulas have bonus effects. For example, the Women’s Hair Growth Nutraceutical can reduce feelings of stress, improve sleep, and lead to thicker brows and lashes. 

An individual bottle of Nutrafol lasts for one month and costs $88. You can sign up for a monthly subscription and receive each bottle for $79. The Hairline Defender Kit is $110, or $98 for a monthly subscription. The Full Support Kit is $157 or $141 for a monthly subscription.

Hers is an telehealth platform aimed at people assigned female at birth that offers prescription support for anxiety, depression, sexual health, and hair loss. Additionally, it has a wide roster of non-prescription wellness products and supplements available to order too. 

It takes the prize for the best prescription pill hair loss treatment due to its easy medical consultation process and affordable monthly fee. The prescription pill offered through the site is oral spironolactone. Spironolactone is a medication that has been used off-label for decades as a hair loss treatment. It is touted for its impressive safety profile and treatment results. If you find a pill isn’t the best fit for you, you can also receive a prescription for a finasteride and minoxidil spray that treats postmenopausal hair loss. 

To get started, you’ll fill out a brief online questionnaire that will ask you more about the hair concerns you’re experiencing. Then you’ll be recommended a product, which may be the oral spironolactone. If you are recommended an oral spironolactone, you will then be prompted to fill out another questionnaire that asks more detailed questions about your health history. You will also be invited to share an image of your hair loss. A medical provider will then review all of your information to ensure the prescription is a good fit before they send it your way. You’re able to stay in touch with your provider for support to ensure your treatment is the right fit for you. 

A prescription for oral spironolactone at Hers begins at $30 per month. The topical finasteride and minoxidil spray begins at $45 per month. Nonprescription supplements, like biotin and 2 percent minoxidil solution, cost $15 to $16 per month. Hers products are not HSA/FSA eligible.

Keep in mind that this service is specifically geared towards people assigned female at birth. If you’re someone assigned male at birth and would like to explore a similar service, check out Hims, the sibling company to Hers.

Sesame simplifies the process of getting prescribed finasteride, a leading treatment for hair loss and prostate enlargement in people assigned male at birth. It offers medical consultations for just $39 and the medication itself costs $5, regardless of if you pick it up at the pharmacy or have it delivered. Sesame is efficient — you can receive a same-day medical consultation and pharmacy pickup. 

Finasteride, which is generic for Propecia, is a popular prescription drug used to treat both prostate enlargement and male hair loss. It is clinically proven to effectively treat hair loss, though it takes three or four months to see any initial results and a total of six to nine months before you see the full effect of the medication on your scalp. Finasteride is a 5-alpha-reductase inhibitor, which allows it to prevent testosterone from converting into the hormone dihydrotestosterone, which is often a culprit for male hair loss. Dihydrotestosterone can also cause prostate enlargement, so this medication may be especially supportive if you’re struggling with both of these issues.

Sesame charges $39 for the mandatory medical consultation where you will be prescribed the Finasteride. The prescription itself is just $5, even with delivery. You can submit your purchase to your HSA/FSA for reimbursement. 

Heads up, though: A major drawback with Sesame is that it is only available in Texas, California, Florida, New York, Pennsylvania, Illinois, Ohio, Georgia, and North Carolina.

Tackling hair thinning with a potent shampoo is an easy way to keep up on your hair loss regimen. However, not all shampoos are the same and some can be filled with harmful chemicals. Pura D’Or ensures all its products are free of parabens, sodium lauryl sulfate, and harmful chemicals. Its M.D. Anti-Hair Thinning Shampoo targets scalp health with coal tar, while biotin is a key active ingredient promoting hair health. Biotin is especially important, says Modglin. “Look for products that either contain minoxidil or that target scalp health, like shampoos and conditioners that include ingredients like biotin, zinc, or saw palmetto,” she says. Don’t be fooled by Pura D’Or’s emphasis on natural ingredients; users provide positive feedback about its ability to boost volume, enhance scalp health, and decrease thinning. Those with dandruff may also find this formula especially helpful since it can bring down scalp irritation and boost hydration.

Another reason why this formula takes the pick for best hair loss shampoo is because it is a good fit for all, regardless of their hair type, and is color safe. This versatility makes it a good fit for those who are challenged to find a product that fits their unique criteria of issues. You may want to pair this shampoo with a moisturizing treatment, since it can be drying, and be aware that it can take a few months to see results. Also, don’t be alarmed by the smell — some users found it off-putting. 

The Pura D’Or M.D. Anti-Hair Thinning Shampoo is $40 for a 16-ounce bottle. It is not HSA/FSA eligible.

Nioxin is considered the leading brand for hair loss treatments, focusing on evidence-based ingredients to help people assigned female and male at birth with all hair types treat excessive hair loss. Its System Kits target various stages of hair thinning. There are six different kits in total, so you can choose which one addresses your concern. System Kit 1 is best suited for natural hair with mild thinning, System Kit 2 is designed for natural hair with significant thinning, System Kit 3 is suitable for color-treated hair with light thinning, System Kit 4 is best for color-treated hair with progressed thinning, System Kit 5 is best for bleached or chemically treated hair in the early stages of thinning, and System Kit 6 can address substantial thinning in bleached or chemically treated hair. 

Aside from the versatility of the kits, it's notable that there are options for those with chemically treated hair. There aren’t a lot of products on the market that are specifically designed to treat hair loss in straightened or relaxed hair, making this a standout feature of the line. 

Ringing in at just $55 for the shampoo, conditioner, and scalp and hair treatment, these kits won’t break the bank. Want to bump up the progress? Add in Nioxin’s 2% Minoxidil Hair Regrowth Treatment to any system. Its active ingredient, 2 percent minoxidil, is clinically proven to efficiently treat hair loss and has decades of research supporting its efficacy.

You can also purchase the best Nioxin System Kit for you through Ulta for $55. Unfortunately, it is not eligible for flexible spending account (FSA) or health saving account (HSA) payments.

The Ordinary’s Multi-Peptide Serum for Hair Density is the best budget hair loss treatment. At just $22, this serum requires only a few drops daily, making the bottle last quite awhile. The Ordinary is known for its roster of affordable yet effective skin and hair treatments that focus on effective clinical formulas. This serum includes caffeine, which is promising for reversing hair thinning. It also includes Redensyl, another formula that is also clinically proven to reduce hair thinning.

Application is easy — just apply a few drops directly to your clean scalp every night and massage it in. There are hundreds of positive user reviews, with many sharing images of their results from just a few months, proving this product can significantly reduce hair thinning. However, some users pointed out that the serum consistency was problematic for their hair type, so those with fine hair beware. 

The Ordinary’s Multi-Peptide Serum for Hair Density costs $22 per bottle plus shipping costs, which will vary based on your location. It is not HSA/FSA eligible. 

Vegamour’s GRO+ Advanced Hair Serum is perfect for those who prefer their products to be rooted in natural ingredients and never tested on animals. The holistic hair brand’s serum uses CBD and plant-based phyto-actives to boost scalp health and increase hair thickness. Part of why the formula is so effective is because of its innovative use of CBD. Rather using the standard form of CBD, this serum uses a smaller cannabidiol molecule, which in turn makes topical absorption easier. It also uses mung bean, red clover, curcumin, and nicotiana benthamiana extracts to boost hair density and thickness. Curcumin, which is the natural anti-inflammatory property present in turmeric, has been shown to be especially supportive for hair regrowth.

In double-blind, in vivo clinical trials conducted by Vegamour, 52 percent of participants reported more density and another 76 percent reported decreased shedding. These results certainly are impressive, though more information on the trial would be welcome; the company’s website doesn’t link to the full study, only a summary of the results. 

Application of Vegamour is super easy: Just fill up the dropper and apply the serum directly to your clean scalp once a day. Make sure your hair is dry, or at least towel-dried. Leave the product in and move forward with styling. The biggest drawback with this product is the price point — it costs $74 for a 1-ounce bottle and it is not HSA/FSA eligible.

Many hair loss treatments are topical formulas, which can lead to greasy hair and uneven application. Plus, some users may not be a fan of getting the treatment on their hands. Keranique’s Hair Regrowth Treatment Extended Nozzle Sprayer solves these dilemmas, offering a spray application and a formula featuring 2 percent minoxidil. “Minoxidil is one of the most common over-the-counter treatments for hair loss because it's FDA-approved, relatively safe, and well-tolerated by most people,” Modglin says. This product offers effective hair treatment by way of minoxidil in a fuss-free application. 

Application is easy, but be prepared to use a good amount of product. You’ll apply six sprays twice a day directly onto the impacted areas. Keep in mind that the bottle is just 2 fluid ounces, and you’ll need to use this product consistently; otherwise, hair loss will begin again. While minoxidil is well-tolerated, side effects like headaches and dermatitis can occur for some, so be sure to consult with your medical provider if anything feels astray. 

Each bottle of Keranique’s Hair Regrowth Treatment Extended Nozzle Sprayer is $29, though if you sign up for auto-replenish, the price drops down to $26. It is not HSA/FSA eligible. 

Rogaine’s 5% Minoxidil Foam for people assigned female at birth is perfect for those who have tried formulas with lower percentages of minoxidil and haven’t had any luck. While other formulas included on this roster of best hair loss treatments only have 2 percent minoxidil, the 5 percent this product offers may result in faster results for some. Its efficacy is promising — Rogaine states it is clinically proven to regrow hair in over 80 percent of people assigned female at birth, according to a 6-month placebo-controlled clinical study. Plus, if you don’t see results after four months of daily use, you can get a refund on the product. Each bottle costs $29 and lasts for two months. 

This may be an excellent choice for those with fine hair. The foam is light and you can style your hair after applying. That being said, be prepared for a potentially messy application process. You’ll have to part your hair into multiple sections and massage the foam into each section. While this particular formula is for women, Rogaine also has a 5 percent minoxidil foam product for men.