Lifestyle Beauty Tips: Treat a Cold Sore By Shape Editors Published on February 5, 2010 Share Tweet Pin Email Treat a Cold Sore Fast fix: Most of the time, the virus that causes fever blisters (HSV-1) lies dormant. But certain triggers, such as stress, exposure to the sun, and hormonal changes, such as PMS, can "awaken" it, causing it to multiply near the surface of your skin. An over-the-counter treatment, like Abreva ($15; drugstore.com) can immediately start shrinking the sore-and in the meantime, dot a concealer on top with a fine-tipped makeup brush to hide it. Was this page helpful? Thanks for your feedback! Tell us why! Other Submit